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  • The Mechanism of activation or inhibition by G Protein-coupled receptors.
This diagram shows a complex which uses the Adenylyl Cyclase pathway with cAMP as a 2nd messenger. This is the mechanism used for signal transduction of many ligands in the human body, including Adrenaline, and Acetylcholine with M2 and M4 Cholinergic receptors. Therefore they are targeted by many drugs, most notably beta-blockers and some Antimuscarinics.

    The Mechanism of activation or inhibition by G Protein-coupled receptors.


    This diagram shows a complex which uses the Adenylyl Cyclase pathway with cAMP as a 2nd messenger.
    This is the mechanism used for signal transduction of many ligands in the human body, including Adrenaline, and Acetylcholine with M2 and M4 Cholinergic receptors. Therefore they are targeted by many drugs, most notably beta-blockers and some Antimuscarinics.

    — 7 months ago with 2 notes
    #Biochemistry  #G protein-coupled 
    1. mdm-arabi posted this